Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Oral Melanotic Macule: Symptoms and Treatment Skinsight Oral Malignant Melanoma Oral Cancer Foundation Information and Resources about Oral Head and Neck Cancer Melanocytic Nevus Vulvovaginal Disorders