An integrative multi omics analysis leveraging Mendelian randomization and subsequent experimental validation prioritizes glutathione S transferase mu 5 (GSTM5) as a genomic stability related gene and a therapeutic vulnerability to PLK1 inhibition in Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega Glutathione in Cancer Cell Death Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification New research targeting senescent zombie" cells highlights potential #cancer therapies reducing inflammation, tumor growth, and treatment related damage through Glutathione Peroxidase 4 (GPX4) inhibition. . Article