Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease Rasburicase Induced Hemolytic Anemia Secondary to Undiagnosed G6PD Deficiency Published in Journal of Brown Hospital Medicine Role of Glucose 6 Phosphate Dehydrogenase (G6PD) in the Pathophysiol ogy of Cataract. Frontiers Glucose 6 Phosphate Dehydrogenase Deficiency and Neonatal Hyperbilirubinemia: Insights on Pathophysiology, Diagnosis, and Gene Variants in Disease Heterogeneity In RBCs, NADPH are produced exclusively via HMP shunt by the action of G6PD and are responsible to maintain membrane integrity preventing premature destruction. That is why G6PD deficient RBCs are