Constantly getting asked about Protandim. Here is my response: Studies show it is helpful in reducing oxidative stress. I don't personally use it in my office, not necessarily because I don't like Metabolic features of cancer cells in NRF2 addiction status Biophysical Reviews Springer Nature Link Frontiers The Role of Natural Products in Targeting Cardiovascular Diseases via Nrf2 Pathway: Novel Molecular Mechanisms and Therapeutic Approaches Phytochemical Activation of Nrf2 Protects Human Coronary Artery Endothelial Cells against an Oxidative Challenge Donovan 2012 Oxidative Medicine and Cellular Longevity Wiley Online Library The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies