Direct Peptides Blog Design, Biological Characterization, and Discovery of Capromorelin Derivatives as Oral Growth Hormone Secretagogue Receptor Type 1a Agonist for the Treatment of Growth Hormone Deficiency Journal of Medicinal Chemistry Figure 3 from Ipamorelin, the first selective growth hormone secretagogue. Semantic Scholar Ipamorelin is a growth hormone releasing peptide, not a growth hormone releasing hormone. That distinction matters. GHRHs like sermorelin signal the pituitary through the natural GHRH receptor, while GHRPs like ipamorelin work Growth Hormone Secretagogue an overview ScienceDirect Topics