VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Approccio Diagnostico terapeutico e Criticit nella Gestione delle VAP Preventing Ventilator Associated Pneumonia Manual of Medicine VAP Guideline Review Preventive bundle approach decreases the incidence of ventilator associated pneumonia in newborn infants Journal of Perinatology